tirzepatide ada ckd in CKD: FDA, ADA, EASD, RSSDI Guidance | Paramesh Shamanna posted on the topic Tirzepatide - an overview Weight Loss/Diabetic Drug Tirzepatide Slashes

Lillys SURPASS-CVOT , providing the first CV-outcomes data for tirzepatide, albeit in T2D patients with established atherosclerotic CV disease and in H2H comparison vs

Key takeaways Retatrutide isn't approved yet and isn't expected to launch in the UK until at least mid-2026 In clinical trials, target doses ranged from 0.5mg to 12mg weekly, with the most common being 4mg, 8mg, 9mg and 12mg Different dosing schedules were tested, with most people starting at 2mg and escalating every 4 weeks The 12mg dose produced the most weight loss (up to 28.7% after 68 weeks) Starting at 2mg rather than 4mg helped reduce side effects during escalation First to know Get an email the day retatrutide launches in the UK

Orlistat: A lipase inhibitor that blocks about one-third of dietary fat from being absorbed (known by brands Alli or Xenical)

For 7.5 mg at 10 mg/mL, draw to 0.75 mL